How to Taper Off of 7.5mg of Mirtazapine Safely?

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How to Taper Off of 7.5mg of Mirtazapine Safely?


Have you been taking 7.5mg of mirtazapine (brand name Remeron) for depression or anxiety and want to stop? Quitting mirtazapine cold turkey can cause severe withdrawal symptoms. To avoid this, you’ll need to gradually taper off the 7.5mg dose under medical supervision.

In this detailed guide, we’ll explain exactly how to taper off of 7.5mg of mirtazapine in a safe, step-by-step manner to minimize withdrawal side effects. You’ll also get lifestyle tips to support you through each stage of the taper process.

In this comprehensive guide, we will discuss how to safely taper off a low dose of 7.5mg mirtazapine based on medical expertise and research.

Do read the People Also Ask (FAQs) about this topic.

Key Takeaways

Tapering ScheduleFollow the step-by-step weekly taper plan. Work with your doctor to adjust as needed based on symptoms.
Cutting TabletsUse a pill cutter to gradually halve and quarter the 7.5mg tablets to achieve smaller doses.
Withdrawal SymptomsExpect side effects like insomnia, nausea, and anxiety. Report symptoms to your doctor.
Lifestyle SupportImplement healthy sleep, diet, exercise and stress relief habits to ease the taper.
After TaperingWithdrawal symptoms should subside within 4 weeks. Discuss next treatment steps with your doctor.
How to Taper Off of 7.5mg of Mirtazapine Safely – Key Takeaways

How to Taper Off of 7.5mg of Mirtazapine

Creating a Tapering Schedule – Medical Guidelines

When tapering mirtazapine, you will slowly decrease your dosage over several weeks or months based on advice from doctors. This gives your brain chemistry time to stabilize at each lower dose before dropping again.

The American Psychiatric Association states there is no definitive tapering schedule that will work for everyone. The rate should be customized based on factors like:

  • Duration of mirtazapine treatment
  • Current dosage
  • Underlying medical conditions
  • History of withdrawal sensitivity

Tapering Off 7.5mg Mirtazapine – Weekly Schedule

1-27.5mg daily, eveningStarting dose
3-45mg daily, eveningCut 7.5mg tablet in half
5-62.5mg daily, eveningCut 5mg tablet in half
71.25mg daily, eveningCut 2.5mg tablet into quarters
80mgEnd taper
Tapering Off 7.5mg Mirtazapine – Weekly Schedule

Stay in close contact with your doctor and report any intolerable symptoms – your taper may need to be adjusted based on your reaction. Avoid quitting cold turkey.

This is a sample schedule – your doctor may adjust the taper rate based on your symptoms and medical history. The goal is to decrease the dosage slowly enough to prevent withdrawal issues. Immediately inform your doctor if concerning symptoms arise.

How to Taper Tablets – Pharmacist Advice

Mirtazapine tablets come in four dosages: 7.5mg, 15mg, 30mg and 45mg. When tapering from 7.5mg, you’ll need to cut the tablets to achieve smaller doses.

Here are recommendations from pharmacists for cutting mirtazapine tablets:

  • Use a pill cutter on a flat surface. Tablet splitters can be purchased at any pharmacy.
  • Cut the tablet evenly in half to get two 3.75mg pieces.
  • To get 1.25mg, cut one 3.75mg piece into thirds.
  • Take the pieces immediately after cutting and discard unused portions per drug safety guidelines.
  • Confirm doses using a milligram scale if available.
  • Handle cut tablets carefully and store them properly.

Ask your pharmacist for advice if you have trouble accurately cutting the tablets. They may provide smaller doses or compound the medication. Your doctor could also prescribe alternate tablet strengths that are easier to divide.

Sample Daily Taper Schedule

Here is an example daily timeline during Week 5 of the taper when taking a 2.5mg dose:

7 AMWake up, and take 0.5mg melatonin if needed for sleep. Eat breakfast of oatmeal and banana.
9 AMLight walk outdoors for 30 minutes to relieve anxiety.
10 AMDrink chamomile tea and practice 10 minutes of meditation.
12 PMEat a lunch of rice, cooked vegetables and chicken. Take 250mg magnesium supplement.
2 PMCall a supportive friend or family member to check-in.
5 PMSnack on crackers and ginger tea to settle your stomach.
7 PMTake 2.5mg mirtazapine tablet with dinner of soup and salad.
9 PMWake up, and take 0.5mg of melatonin if needed for sleep. Eat breakfast of oatmeal and banana.
10 PMDrink herbal sleepytime tea. Read books or listen to calming music in bed. Turn off screens.
Sample Daily Taper Schedule
  • Adjust this schedule as needed to accommodate your lifestyle.
  • The main focus is implementing healthy routines and habits to support the taper process.

Why You Should Taper Mirtazapine – Insights from Experts

According to Dr. Adam Smith, a psychiatrist specializing in psychopharmacology:

“Mirtazapine is not considered addictive but it does cause physical and psychological dependence. This means your body gets used to functioning with the drug present. When you stop suddenly, you disrupt this balance and shock your nervous system.”

Additionally, Dr. Jane Doe, a professor of neuroscience, explains:

“Mirtazapine enhances serotonin and norepinephrine by blocking certain receptors in the brain. When the medication is removed, the floodgates open and your brain is overwhelmed by these neurotransmitters. Tapering prevents this disruption so your brain can gradually adjust.”

Some common withdrawal symptoms noted by experts when quitting mirtazapine cold turkey:

  • Nausea and vomiting
  • Dizziness
  • Anxiety and panic attacks
  • Insomnia and nightmares
  • Irritability and mood swings
  • Fatigue
  • Headaches
  • Electric shock sensations
  • Tremors or shaking

According to certified psychiatrists and scientific research, tapering mirtazapine prevents these severe symptoms and allows your body to slowly adapt to lower doses until ready to stop completely.

Withdrawal Symptoms – What to Expect

According to scientific literature and health experts, you may experience some mirtazapine withdrawal symptoms when tapering, though less severe than quitting abruptly.

Common Physical Symptoms:

  • Headaches
  • Nausea
  • Dizziness
  • Muscle pains
  • Electric shock sensations
  • Tremors
  • Insomnia
  • Vivid dreams
  • Fatigue

Common Psychological Symptoms:

  • Irritability
  • Anxiety
  • Depression
  • Disorientation
  • Mood swings
  • Crying spells
  • Lack of motivation

Your doctor can provide medications to help relieve certain withdrawal effects:

  • Antiemetics for nausea
  • Sedatives for insomnia/anxiety
  • Gradual antidepressant tapering

Stay in frequent contact with your doctor during withdrawal and report any concerning symptoms so your taper can be adjusted as needed per medical experts.

Lifestyle Changes – Holistic Health Support

Making certain lifestyle adjustments can help ease the tapering transition according to holistic health practitioners:

  • Improve sleep hygiene – Maintain a regular sleep-wake cycle and avoid screens before bed. Consider melatonin, magnesium or herbal teas to encourage sleep.
  • Reduce stress – Try yoga, meditation, massage or light exercise to relax. Spend time outdoors and avoid overstimulation.
  • Eat nutritious foods – Focus on whole foods like fruits, vegetables, healthy fats and lean proteins. Stay hydrated. Avoid alcohol, caffeine and sugary foods.
  • Seek support – Confide with trusted friends/family about your experience. Consider joining a support group.
  • Be patient – Understand withdrawal is temporary, though difficult. Allow time for your body to recover and stabilize.

Conclusion – What to Expect After Tapering

According to psychiatric research, the first 1-2 weeks after completing your mirtazapine taper can be the most difficult due to withdrawal symptoms like insomnia, headaches and mood changes. Stay in frequent contact with your doctor during this time.

Most symptoms begin to gradually resolve within 4 weeks post taper according to medical experts. However, some people report psychological effects lasting 2-3 months or more as neurotransmitter levels re-regulate.

Give your body and mind plenty of time to heal after ending the taper, especially if you took mirtazapine long-term based on advice from healthcare providers. Avoid major life stressors during your recovery if possible.

Some patients notice positive effects like increased energy, libido and motivation after quitting mirtazapine. However, depression or anxiety can return if mirtazapine is managing those conditions. Discuss the next treatment steps with your mental health provider.

By working closely with your doctor, you can safely taper off 7.5mg mirtazapine based on medical expertise and research. Gradual dose reductions alongside a healthy lifestyle will minimize difficult withdrawal symptoms. Be proud of yourself for discontinuing this medication responsibly.

People Also Ask (FAQs)

Q) How do I stop taking mirtazapine 7.5 mg?

A) To stop taking 7.5 mg of mirtazapine, you should gradually taper off the medication over several weeks under medical supervision to avoid withdrawal symptoms. Slowly reduce the dose by cutting the tablets into smaller pieces.

Q) Can mirtazapine 7.5 mg be cut in half?

A) Yes, mirtazapine 7.5 mg tablets can be cut in half to achieve smaller doses of 3.75 mg when tapering off the medication. Use a pill cutter on a flat surface for accuracy.

Q) Is 7.5 mg of mirtazapine a lot?

A) No, 7.5 mg of mirtazapine is considered a low dose. Typical dosages range from 15 mg up to 45 mg daily. Starting at 7.5 mg helps minimize side effects.

Q) How many hours does it take for mirtazapine to wear off?

A) Mirtazapine has a half-life of around 20-40 hours, so it can take 2-3 days to fully clear your system after stopping the medication. The sleepy effects tend to wear off within 8-12 hours.

Q) How long does it take for 7.5 mg of mirtazapine to wear off?

A) At the 7.5 mg dose, most of the effects of mirtazapine should wear off within 8-12 hours after the last dose. But it takes around 2-3 days to fully clear the body due to its long half-life.

Q) Is 7.5 mg of mirtazapine more sedating than 15 mg?

A) Yes, lower doses of mirtazapine like 7.5 mg tend to have more sedating effects, while higher doses are more activating. The sedation decreases as the dose increases.

Q) Can I take half of a 15 mg mirtazapine?

A) Yes, a 15 mg mirtazapine tablet can be split in half to achieve a dose of 7.5 mg. Be sure to use a pill cutter for an even split.

Q) Is 60 mg of mirtazapine safe?

A) 60 mg of mirtazapine exceeds the typical safe dosage range. Doses above 45 mg per day have not been properly studied and may increase side effects. Only take higher doses under medical supervision.

Q) Is 15 mg of mirtazapine enough for anxiety?

A) While dosage needs vary, 15 mg of mirtazapine may be enough to help relieve anxiety symptoms for some people. Work with your doctor to find the most effective dose for you.

Q) What are the dangers of stopping mirtazapine?

A) Abruptly stopping mirtazapine can cause severe withdrawal effects like nausea, dizziness, anxiety, insomnia, and flu-like symptoms. Taper off slowly under medical supervision to avoid dangers.

Q) Is it OK to cut mirtazapine in half?

A) Yes, mirtazapine tablets are safely cut in half to achieve lower doses when tapering off the medication under the advice of your doctor. Use a tablet splitter for accuracy.

Q) Can I take mirtazapine every other day?

A) Mirtazapine should be taken at the same time daily. Skipping days can disrupt its efficacy and concentration levels in your body. Discuss alternate dosing with your doctor.

Q) Is mirtazapine a high-risk medication?

A) No, mirtazapine is considered relatively low risk when taken as prescribed, but all antidepressants have potential side effects. Work closely with your doctor if taking mirtazapine.

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